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Kindai University Hospital   Department of Clinical Laboratory Medicine























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教授 上硲 俊法

研究業績(2007年以降)

著書

(分担執筆)上硲俊法 生涯教育のためのセルフトレーニング問題と解説、編集:日本内科学会(専門医部会)、2008.3.20. 医学書院、pp4-13 


(分担執筆)Toshinori Kamisako  Chapter 11. Hyperbilirubinemia InDiagnosis of Liver Disease. Pathological Findings, Clinical Manifestations, and Image Analyses. Ed) Masaki Iwai, pp155-168, 2011. McGraw-Hill.


(分担執筆)上硲俊法他 Dubin-Johnson症候群 新領域別症候群20 先天性代謝異常症候群(第2版)下 別冊 日本臨床 2012.12.20   pp348-352.

(分担執筆)上硲俊法他 リポ蛋白分画精密測定 日本臨床 2013



(分担執筆)上硲俊法 体質性黄疸 「内科学」第10版 編集:矢崎義雄 2013.6.10 朝倉書店     pp1154-1156 

(分担執筆)上硲俊法他 先天性高ビリルビン血症 (体質性黄疸)「内科学書」第8版4巻 
  総編集:小川聡 2013.10.30 中山書店 pp294-298 



(分担執筆)上硲俊法他 第1章異常値深読みグレードアップ15.アミラーゼ高値「考える臨床検査」
  文光堂 2015年05月 

(分担執筆)上硲俊法他 第11章脂質 コレステロール ②コレステロール分画、リポ蛋白分画
 「糖尿病を診るポケット検査事典」 医歯薬出版株式会社 2016年05月 



(分担執筆)上硲俊法他 9.肝・胆道の疾患 9-11体質性黄疸 
 「内科学」第11版 朝倉書店  2017年03月 


(監修)上硲俊法 薬剤師のための基礎からの検査値の読み方  じほう 2018年09月 

(分担執筆)上硲俊法 Diagnosis of Liver Disease. Chapter 13 Hyperbilirubinemia,       Springer,   2019年 

論文

Toshinori Kamisako, and Hiroshi Ogawa. Effect of bile duct obstruction on the expression ofintestinal mRNA related to cholesterol and bile acid metabolism in the rat. J Gastroenterol Hepatol, 2007;22: 125-131.

Hiroshi Ogawa, Yukiko Okada , Toshinori Kamisako, Kimie Baba. Beneficial effect of xanthoangelol, a chalcone compound from Angelica Keiskei, on lipid metabolism in stroke-prone spontaneously hypertensive rats. Clin Exp Pharmacol Physiol, 2007; 34: 238-43.

Hiroshi Ogawa, Noriko Sasai, Toshinori Kamisako, Kimie Baba. Effects of osthol on blood pressure and lipid metabolism in stroke-prone spontaneously hypertensive rats. J Ethnopharmacol. 2007; 112: 26-31.

Toshinori Kamisako, Hiroshi Ogawa, Kazuo Yamamoto. Effect of cholesterol, cholic acid and cholestyramine administration on the intestinal mRNA expressions related to cholesterol and bile acid metabolism in the rat. J Gastroenterol Hepatol. 2007;22: 1832-1837.

Atsushi Kotani, Yutaka Hirano, Nakamura Hajime, Yumiko Tsuji, Naitoh Shouchi, Toshinori Kamisako, Kinji Ishikawa. Myocardial stain imaging in a patient with secondary hemochromatosis. J Echocardiography, 2007; 5: 84-87.

Kohsaku Uetani, Miki Hiroi, Tadamichi Meguro, Hiroshi Ogawa, Toshinori Kamisako, Yoshihiro Ohmori, Serpil C. Erzrum. Influenza A virus abrogates IFN-gamma response in respiratory epitherial cells by disruption of Jak/Statpathway. Eur. J Immunol 2008; 38: 1559-1573.

Toshinori Kamisako Present status of drug-induced liver injury (DILI) in Japan. Is a proposed diagnostic scale useful?  Hepetology Research 2009; 39: 949-950.

Yoshizumi Kishino, Yuji Tanaka, Shouchi Naitoh, Toshinori Kamisako. Danazol Falsely Increased Values in Estradiol Immunoassays. Clin Chim Acta 2010 411:1380-1.

Inaba T, Yuki Y, Yuasa S, Fujita N, Yoshitomi K, Kamisako T, Torii K, Okada T, Urasaki Y, Ueda T, Tohyama K. Clinical utility of the neutrophil distribution pattern obtained using the CELL-DYN SAPPHIRE hematology analyzer for the diagnosis of myelodysplastic syndrome.  Int J Hematol. 2011; 91: 169-177.

Toshinori Kamisako, Yuji Tanaka, Takanori Ikeda, Kazuo Yamamoto, Hiroshi Ogawa. Dietary fish oil regulates gene expression of cholesterol and bile acid transporters in mice. Hepatol Res 2012; 42:321-326.

Yuji Tanaka, Takanori Ikeda, Kazuo Yamamoto, Hiroshi Ogawa, and Toshinori Kamisako. Dysregulated expression of fatty acid oxidation enzymes and iron-regulatory genes in livers of Nrf2-null mice. J Gastroenterol Hepatol 2012;

Toshinori Kamisako, Shiori Masuda, and Yuji Tanaka. Relationship between serum bilirubin and remnant lipoprotein cholesterol level. Clin Lab 59(3-4):435-8.2013

Yoshizumi Kishino ,Yuji Tanaka, Takanori Ikeda, Kazuo Yamamoto, Hiroshi Ogawa, Yoshinori Iwatani, Toshinori Kamisako. Ezetimibe increases hepatic iron levels in mice fed a high-fat diet J Pharmacol Exp Ther345(3):483-91 2013

Toshinori Kamisako,Yuji Tanaka,Yoshizumi Kishino , Takanori Ikeda, Kazuo Yamamoto, Shiori Masuda,Hiroshi Ogawa. Role of Nrf2 in the alteration of cholesterol and bile acid metabolism -related gene expression by dietary cholesterol in high fat-fed mice.J Clin Biochem Nutr 54(2):90-94 2014

Ikeda Takanori, Tanaka Yuji, Yamamoto Kazuo, Morii Hiroko, Kamisako Toshinori , Ogawa Hiroshi. Geranium dielsianum extract powder (MISKAMISKA (TM)) improves the intestinal environment through alteration of microbiota and microbial metabolites in rats, JOURNAL OF FUNCTIONAL FOODS, 11, 12, 19,   2014年11月, 査読有り

Masuda S, Ichihara K, Yamanishi H, Hirano Y, Tanaka Y, Kamisako T. Evaluation of menstrual cycle-related changes in 85 clinical laboratory analytes. Scientific Committee for Asia-Pasific Federation of Clinical Biochemistry., Annals of clinical biochemistry, 53, Pt 3, 365, 376,   2016年05月, 査読有り

Tanaka Y, Ikeda T, Yamamoto K, Masuda S, Ogawa H, Kamisako T. 6-Methylsulfinylhexyl isothiocyanate prevents high-fat diet-induced fatty liver but fails to attenuate hepatic iron accumulation in mice., Clinical and experimental pharmacology & physiology, 43, 11, 1153, 1156,   2016年11月, 査読有り

Imoto M, Yoshida K, Maeda Y, Nakae K, Kudo M, Sakurabayashi I, Yamada T, Kamisako T . A Case of Waldenstrom Macroglobulinemia with Temporary Appearance of 7S IgM Half Molecule. Clinical laboratory, 63, 5, 983, 989,   2017年05月, 査読有り>

Toda H, Satoh K, Komatsu M, Fukuda S, Nakamura T, Jikimoto T, Nishio H, Yamasaki K, Maede T, Orita T, Sueyoshi N, Kita M, Toyokawa M, Nishi I, Akagi M, Higuchi T, Kofuku T, Nakai I, Ono T, Shimakawa K, Hikita Y, Moro K, Kida K, Oohama M, Wada Y, Tobe T, Kamisako T, Tanaka Y. Laboratory surveillance of antimicrobial resistance and multidrug resistance among Streptococcus pneumoniae isolated in the Kinki region of Japan, 2001-2015., Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 24, 3, 171, 176,   2018年03月, 査読有り

Tanaka Y, Ikeda T, Yamamoto K, Masuda S, Ogawa H, Kamisako T. Gender-divergent expression of lipid and bile acid metabolism related genes in adult mice offspring of dams fed a high-fat diet., Journal of biosciences, 43, 2, 329, 337,   2018年06月, 査読有り

Toda H, Tanaka Y, Satoh K, Wada Y, Tobe T, Kamisako T. Epidemiological and molecular characterization of invasive Streptococcus pneumoniae isolated following introduction of 7- valent conjugate vaccine in Kinki region, Japan, 2008-2013. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 26, 3, 451,458,   2020年03月, 査読有り

Tanaka Y, Ikeda T, Ogawa H, Kamisako T. Ezetimibe markedly reduces hepatic triglycerides and cholesterol in rats fed on fish oil by increasing the expression of cholesterol efflux transporters. The Journal of Pharmacology and Experimental Therapeutics, 374, 175, 183    2020年07月, 査読有り

   2006年以前の業績

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