RESEARCH研究

研究業績・論文発表

論文

Hiroki Mizusawa , Hisako Matsumoto , Masashi Shiraishi , Ryuji Sugiya , Yu Takeda , Masaya Noguchi , Tamotsu Kimura , Akira Ishikawa , Osamu Nishiyama , Yuji Higashimoto

Evaluation of patients with chronic obstructive pulmonary disease by maximal inspiratory pressure and diaphragmatic excursion with ultrasound sonography

Respir Investig. 2024 Mar

Ryuji Sugiya , Shinichi Arizono , Yuji Higashimoto 1, Yuta Kimoto 1, Masashi Shiraishi 1, Hiroki Mizusawa 1, Yuichi Tawara 2, Hironori Shigeoka 3, Jan Bakker 4 5 6 7, Koichiro Shinozaki

Association of tissue oxygen saturation levels with skeletal muscle injury in the critically ill

Sci Rep 2024 Feb 27

Masashi Shiraishi, Yuji Higashimoto, Ryuji Sugiya, Hiroki Mizusawa, Yu Takeda, Masaya Noguchi, Osamu Nishiyama, Ryo Yamazaki, Shintarou Kudo, Tamotsu Kimura, Yuji Tohda, Hisako Matsumoto

Diaphragm dome height on chest radiography as a predictor of dynamic lung hyperinflation in COPD

ERJ Open Research 2023.9

Shiraishi, M., Y. Higashimoto, R. Sugiya, H. Mizusawa, Y. Takeda, S. Fujita, O. Nishiyama, S. Kudo, T. Kimura, K. Fukuda and Y. Tohda

Sternocleidomastoid Muscle Thickness Correlates with Exercise Tolerance in Patients with COPD

Respiration 2023

Itokazu, M., Onodera, Y., Mori, T., Inoue, S., Yamagishi, K., Moritake, A., Iwawaki, N., Shigi, K., Takehara, T., Higashimoto, Y., Akagi, M. and Teramura, T.

Adipose-derived exosomes block muscular stem cell proliferation in aged mouse by delivering miRNA Let-7d-3p that targets transcription factor HMGA2.

J Biol Chem. 2022;298(7):102098.

M. Itokazu, Y. Higashimoto, M. Ueda, K. Hanada, S. Murakami and K. Fukuda

Effectiveness of Rehabilitation for Cancer Patients with Bone Metastasis.

Prog Rehabil Med. 2022;7:20220027.

Masashi Shiraishi, Yuji Higashimoto, Ryuji Sugiya, Hiroki Mizusawa, Yu Takeda, Shuhei Fujita, Osamu Nishiyama, Shintarou Kudo, Tamotsu Kimura, Yasutaka Chiba, Kanji Fukuda, Yuji Tohda, Hisako Matsumoto

Diaphragmatic excursion is correlated with the improvement in exercise tolerance after pulmonary rehabilitation in patients with chronic obstructive pulmonary disease.

Respiratory research 2021;22: 271-271.

Yuji Higashimoto, Masashi Shiraishi, Ryuji Sugiya, Hiroki Mizusawa, Osamu Nishiyama, Yamazaki Ryo, Takashi Iwanaga, Yasutaka Chiba, Yuji Tohda, Kanji Fukuda

Effect of Pulmonary Rehabilitation on Erector Spinae Muscles in Individuals With COPD.

Respiratory care 2021;66:1458-1468.

Ryuji Sugiya, Yuji Higashimoto, Masashi Shiraishi, Tomomi Tamura, Tamotsu Kimura, Yasutaka Chiba, Osamu Nishiyama, Shinichi Arizono, Kanji Fukuda, Yuji Tohda

Decreased Tongue Strength is Related to Skeletal Muscle Mass in COPD Patients.

Dysphagia 2021 in press

Hiroyuki Kawamura, Shimon Tasaka, Atsutoshi Ikeda, Takashi Harada, Yuji Higashimoto, Kanji Fukuda

Ability to categorize end-feel joint movement according to years of clinical experience: an experiment with an end-feel simulator.

Journal of physical therapy science 2020:32: 297-302.

Yuji Higashimoto , Morihide Ando , Akiko Sano , Sho Saeki , Yusaku Nishikawa , Kanji Fukuda , Yuji Tohda

Effect of pulmonary rehabilitation programs including lower limb endurance training on dyspnea in stable COPD: A systematic review and meta-analysis

Respir Investig. 2020 Sep;58(5):355-366.

Masashi Shiraishi, Yuji Higashimoto, Ryuji Sugiya, Hiroki Mizusawa, Yu Takeda, Shuhei Fujita, Osamu Nishiyama, Shintarou Kudo, Tamotsu Kimura, Yasutaka Chiba, Kanji Fukuda, Yuji Tohda

Diaphragmatic excursion correlates with exercise capacity and dynamic hyperinflation in COPD patients

ERJ Open Res. 2020 Dec 21;6(4):00589-2020

Higashimoto Y, Sano A, Nishiyama O, Sano H, Iwanaga T, Haraguchi R, Chiba Y, Fukuda K, Tohda Y.

Prefrontal cortex activation is associated with dyspnea during methacholine bronchial provocation tests in patients with bronchial asthma.

Allergol Int. 2020 Feb 26. pii: S1323-8930(19)30202-3.

Acute effects of intravenous carvedilol versus metoprolol on baroreflex-mediated sympathetic circulatory regulation in rats.

Int J Cardiol. 2019 Jun 15;285:65-71. doi: 10.1016/j.ijcard.2019.02.062. Epub 2019 Mar 4.

Effects of the rotigotine transdermal patch versus oral levodopa on swallowing in patients with Parkinson's disease.

J Neurol Sci. 2019 Sep 15;404:5-10. doi: 10.1016/j.jns.2019.07.003. Epub 2019 Jul 9.

Yamamoto H, Kawada T, Shimizu S, Uemura K, Inagaki M, Kakehi K, Iwanaga Y, Fukuda K, Miyamoto T, Miyazaki S, Sugimachi M.

Ivabradine does not acutely affect open-loop baroreflex static characteristics and spares sympathetic heart rate control in rats.

Int J Cardiol. 2018 Apr 15;257:255-261. doi: 10.1016/j.ijcard.2017.11.115.

Factors associated with the effect of pulmonary rehabilitation on physical activity in patients with chronic obstructive pulmonary disease.

Geriatr Gerontol Int. 17(1):17-23, 2017. doi: 10.1111/ggi.12656.
慢性閉塞性肺疾患のリハビリテーションにおける精神面の関与を証明した。

Effect of a postoperative outpatient pulmonary rehabilitation program on physical activity in patients who underwent pulmonary resection for lung cancer.

Geriatr Gerontol Int. 16(5):550-5, 2016. doi: 10.1111/ggi.12505.
肺切除周術期における呼吸リハビリテーションの有用性を証明した。

Influence of comorbidities on the efficacy of pulmonary rehabilitation in patients with chronic obstructive pulmonary disease.

Geriatr Gerontol Int. 16(8):934-41, 2016. doi: 10.1111/ggi.12575.
慢性閉塞性呼吸障害に対するリハビリテーションの障害因子を明らかにした。

Exertional dyspnoea and cortical oxygenation in patients with COPD.

Eur Respir J. 46(6):1615-24, 2015. doi: 10.1183/13993003.00541-2015.
慢性閉塞性呼吸障害における呼吸困難感の中枢における調節機構を見いだした。