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〒589-8511 大阪府大阪狭山市大野東377-2

研究業績PUBLICATION LIST

2022年

 Manabu Kawata, Takeshi Teramura, Philip Ordoukhanian, Steven R Head, Padmaja Natarajan, Aishwarya Sundaresan, Merissa Olmer, Hiroshi Asahara, and Martin K Lotz.
Krüppel-like factors-4 and -2 are important regulators of joint tissue cells and protect against tissue destruction and inflammation in osteoarthritis. Annals of the Rheumatic Diseases. 2022 in press.



Sueyoshi Y, Niwa A, Itani Y, Yamauchi M, Asamura S, Teramura T, Isogai N.
Surface modification of the cubic micro-cartilage by collagenase treatment and its efficacy in cartilage regeneration for ear tissue engineering. Int J Pediatr Otorhinolaryngol. 2022 Feb;153:111037. doi: 10.1016/j.ijporl.2021.111037. Epub 2022 Jan 3. PMID: 34998203.



Kuwahara M, Akasaki Y, Kurakazu I, Sueishi T, Toya M, Uchida T, Tsutsui T, Hirose R, Tsushima H, Teramura T, Nakashima Y.
C10orf10/DEPP activates mitochondrial autophagy and maintains chondrocyte viability in the pathogenesis of osteoarthritis. FASEB J. 2022 Feb;36(2):e22145. doi: 10.1096/fj.202100896R. PMID: 34997944.



Mori T, Onodera Y, Itokazu M, Takehara T, Shigi K, Iwawaki N, Akagi M, Teramura T.
Depletion of NIMA-related kinase Nek2 induces aberrant self-renewal and apoptosis in stem/progenitor cells of aged muscular tissues. Mech Ageing Dev. 2022 Jan;201:111619. doi: 10.1016/j.mad.2022.111619. Epub 2022 Jan 4. PMID:34995645.


2021年

Suzuki S, Yonesaka K, Teramura T, Takehara T, Kato R, Sakai H, Haratani K,Tanizaki J, Kawakami H, Hayashi H, Sakai K, Nishio K, Nakagawa K.
KRAS Inhibitor Resistance in MET-Amplified KRASG12C Non-Small Cell Lung Cancer Induced By RAS- and Non-RAS-Mediated Cell Signaling Mechanisms. Clin Cancer Res. 2021 Oct 15;27(20):5697-5707. doi: 10.1158/1078-0432.CCR-21-0856. Epub 2021 Aug 7. Erratum in: Clin Cancer Res. 2022 Jan 15;28(2):428. PMID: 34365406.



Hirano N, Kusuhara H, Sueyoshi Y, Teramura T, Murthy A, Asamura S, Isogai N, Jacquet RD, Landis WJ.
Ethanol treatment of nanoPGA/PCL composite scaffolds enhances human chondrocyte development in the cellular microenvironment of tissue-engineered auricle constructs. PLoS One. 2021 Jul 9;16(7):e0253149. doi: 10.1371/journal.pone.0253149. PMID: 34242238; PMCID: PMC8270150.



Sakai H, Kawakami H, Teramura T, Onodera Y, Somers E, Furuuchi K, Uenaka T, Kato R, Nakagawa K.
Folate receptor α increases chemotherapy resistance through stabilizing MDM2 in cooperation with PHB2 that is overcome by MORAb-202 in gastric cancer. Clin Transl Med. 2021 Jun;11(6):e454. doi: 10.1002/ctm2.454. PMID: 34185411; PMCID: PMC8167866



Sueyoshi Y, Isogai N, Nagumo Y, Onodera Y, Teramura T, Asamura S, Kusuhara H.
Efficacy of sliced nerves of different thickness in a biodegradable nerve conduit to promote Schwann cell migration and axonal growth: An experimental study in the rat model. Microsurgery. 2021 Jul;41(5):448-456. doi: 10.1002/micr.30757. Epub 2021 May 19. PMID: 34008859.

2020年

Tsujimoto T, Mori T, Houri K, Onodera Y, Takehara T, Shigi K, Nakao S, Teramura T, Fukuda K.
miR-155 inhibits mitophagy through suppression of BAG5, a partner protein of PINK1.
Biochem Biophys Res Commun. 2020 Mar 12;523(3):707-712. doi: 10.1016/j.bbrc.2020.01.022. Epub 2020 Jan 14. PubMed PMID: 31948758.



Houri K, Mori T, Onodera Y, Tsujimoto T, Takehara T, Nakao S, Teramura T, Fukuda K.
miR-142 induces accumulation of reactive oxygen species (ROS) by inhibiting pexophagy in aged bone marrow mesenchymal stem cells.
Sci Rep. 2020 Feb 28;10(1):3735. doi: 10.1038/s41598-020-60346-2. PubMed PMID: 32111926; PubMed Central PMCID: PMC7048811.



2019年

Onodera Y, Teramura T, Takehara T, Fukuda K.
Transforming Growth Factor
β-Activated Kinase 1 Regulates Mesenchymal Stem Cell Proliferation Through Stabilization of Yap1/Taz Proteins.
Stem Cells. 2019 Dec;37(12):1595-1605. doi: 10.1002/stem.3083. Epub 2019 Nov 18. PubMed PMID: 31461199; PubMed Central PMCID: PMC6916189.



Horita M, Nishida K, Hasei J, Furumatsu T, Sakurai M, Onodera Y, Fukuda K, Salter DM, Ozaki T.
Involvement of ADAM12 in Chondrocyte Differentiation by Regulation of TGF-β1-Induced IGF-1 and RUNX-2 Expressions.
Calcif Tissue Int. 2019 Jul;105(1):97-106. doi: 10.1007/s00223-019-00549-6. Epub 2019 Apr 16. PubMed PMID: 30993375.



2018年

Onodera Y, Teramura T, Takehara T, Itokazu M, Mori T, Fukuda K.
Inflammation-associated miR-155 activates differentiation of muscular satellite cells.
PLoS One. 2018 Oct 1;13(10):e0204860. doi: 10.1371/journal.pone.0204860. eCollection 2018. PubMed PMID: 30273359; PubMed Central PMCID: PMC6166968.


Teramura T, Matsuda K, Takehara T, Shinohara K, Miyashita Y, Mieno Y, Mori T, Fukuda K, Suzuki K, Suemori H.
Laser-assisted cell removing (LACR) technology contributes to the purification process of the undifferentiated cell fraction during pluripotent stem cell culture.
Biochem Biophys Res Commun. 2018 Sep18;503(4):3114-3120.doi:10.1016/j.bbrc.2018.08.101.Epub 2018 Aug 22. PubMed PMID: 30143262.


Teramura T, Onodra Y.
Stem cell depletion by inflammation-associated miR-155.
Aging (Albany NY). 2018 Jan 23;10(1):17-18. doi: 10.18632/aging.101374. PubMed PMID: 29362291; PubMed Central PMCID: PMC5811257.


2017年

Onodra Y, Teramura T, Takehara T, Obora K, Mori T, Fukuda K.
miR-155 induces ROS generation through downregulation of antioxidation-related genes in mesenchymal stem cells.
Aging Cell. 2017 Dec;16(6):1369-1380. doi: 10.1111/acel.12680. Epub 2017 Oct 2. PubMed PMID: 28967703; PubMed Central PMCID: PMC5676067.


Honda H, Gotoh M, Kanazawa T, Ohzono H, Nakamura H, Ohta K, Nakamura KI, Fukuda K, Teramura T, Hashimoto T, Shichijo S, Shiba N.
Accelerates Tendon-to-Bone Healing After Rotator Cuff Repair.
Am J Sports Med.2017 Dec;45(14):3322-3330. doi: 10.1177/0363546517720199. Epub 2017 Sep 5. PubMed PMID: 28872895.


Obora K, Onodera Y, Takehara T, Frampton J, Hasei J, Ozaki T, Teramura T, Fukuda K.
Inflammation-induced miRNA-155 inhibits self-renewal of neural stem cells via suppression of CCAAT/enhancer binding protein β (C/EBPβ) expression.
Sci Rep. 2017 Feb 27;7:43604. doi: 10.1038/srep43604. PMID: 28240738


Hasei J,Teramura T, Takehara T, Onodera Y, Horii T, Olmer M, Hatada I, Fukuda K, Ozaki T, Lotz MK, Asahara H.
TWIST1 induces MMP3 expression through up-regulating DNA hydroxymethylation and promotes catabolic responses in human chondrocytes.
Scientific Reports. 2017 Feb 21;7:42990. doi: 10.1038/srep42990.PubMed PMID: 28220902; PubMed Central PMCID: PMC5318945.

2015年

Toshiyuki Takehara, Teramura Takeshi, Yuta Onodera, John Frampton and Kanji Fukuda.
Cdh2 stabilizes FGFR1 and contributes to primed-state pluripotency in mouse epiblast stem cells.
Scientific Reports. Sci Rep. 2015 Sep 30;5:14722. doi: 10.1038/srep14722. PMID: 26420260.


Onodera Y, Teramura T, Takehara T, Shigi K, Fukuda K.
Reactive oxygen species induce Cox-2 expression via TAK1 activation in synovial fibroblast cells.
FEBS Open Bio. 2015 Jun 6;5:492-501. doi: 10.1016/j.fob.2015.06.001. eCollection 2015. PubMed PMID: 26110105


Onodera Y, Teramura T, Takehara T, Fukuda K.
Hyaluronic Acid Regulates a Key Redox Control factor Nrf2 via Phosphorylation of Akt in Bovine Articular Chondrocyte.
FEBS Open Bio. 2015 May 29;5:476-84. doi: 10.1016/j.fob.2015.05.007. eCollection 2015. PubMed PMID: 26106522



2013年

Tsukamoto I, Inoue S, Teramura T, Takehara T, Ohtani K, Akagi M.
Activating types 1 and 2 angiotensin II receptors modulate the hypertrophic differentiation of chondrocytes.
FEBS Open Bio. 2013 Jul 4;3:279-84. PubMed PMID: 23905010


Onodera Y, Teramura T, Takehara T, Fukuda K.

c-Jun N-terminal kinase (JNK) mediates Rho/ROCK induced Sox9 diminution in chondrocytes. Acta Medica Kinki University 巻38 No.2 2013

2012年

Teramura T, Sugimoto H, Frampton J, Kida Y, Nakano M, Kawakami M, Izumi H, Fukunaga N, Onodera Y, Takehara T, Fukuda K, Hosoi Y.
Generation of Embryonic Stem Cell Lines from Immature Rabbit Ovarian Follicles.
Stem Cells Dev. 2012 Oct 16. [Epub ahead of print]
PubMed PMID: 23072728.


Teramura T, Onodera Y, Takehara T, Frampton J, Matsuoka T, Ito S, Nakagawa K, Miki Y, Hosoi Y, Hamanishi C, and Fukuda K.
Induction of Functional Mesenchymal Stem Cells in Severe Hypoxic Condition from Rabbit Embryonic Stem Cells.
Cell Transplantation. 2012 in press.


Nakagawa K, Teramura T, Takehara T, Onodera Y, Hamanishi C, Akagi M, Fukuda K.
Cyclic compression-induced p38 activation and subsequent MMP13 expression requires Rho/ROCK activity in bovine cartilage explants.
Inflamm Res. 2012 Jun 12. [Epub ahead of print] PubMed PMID: 22688963.


Fukunaga N, Teramura T, Hosoi Y.
Embryonic Stem Cells: A Novel Attractive Research Tool for Germ Cell Development(review).
J. Mamm. Ova. Res. 2012 in press.

2011年

Teramura T, Takehara T, Onodera Y, Nakagawa K, Hamanishi C, Fukuda K.
Mechanical stimulation of cyclic tensile strain induces reduction of pluripotent related gene expressions via activation of Rho/ROCK and subsequent decreasing of AKT phosphorylation in human induced pluripotent stem cells.
Biochem Biophys Res Commun. 2012 Jan13;417(2):836-41. Epub 2011 Dec 20. PubMed PMID:22206673.


Takehara T, Teramura T, Onodera Y, Hamanishi C, Fukuda K.
Reduced oxygen concentration enhances conversion of embryonic stem cells to epiblast stem cells.
Stem Cells Dev. 2012 May 20;21(8):1239-49. Epub 2011 Oct 18.PubMed PMID:21861689.

2010年

Fukunaga N, Teramura T, Onodera Y, Takehara T, Fukuda K, Hosoi Y. Leukemia inhibitory factor (LIF) enhances germ cell differentiation from primate embryonic stem cells.
Cell Reprogram. 2010 Aug;12(4):369-76. PubMed PMID:20698776.


Teramura T, Onodera Y, Mihara T, Hosoi Y, Hamanishi C, Fukuda K.
Induction of mesenchymal progenitor cells with chondrogenic property from mouse-induced pluripotent stem cells.
Cell Reprogram. 2010 Jun;12(3):249-61. PubMed PMID:20698767.


Nagai N, Kawao N, Okada K, Okumoto K, Teramura T, Ueshima S, Umemura K, Matsuo O.
Systemic transplantation of embryonic stem cells accelerates brain lesion decrease and angiogenesis.
Neuroreport. 2010 Jun 2;21(8):575-9. PubMed PMID:20431496.


Onodera Y, Teramura T, Ozawa M, Takehara T, Mitani T, Anzai M, Sagawa N, Hamanishi C, Hosoi Y, Fukuda K.
Differentiation diversity of mouse parthenogenetic embryonic stem cells in chimeric mice.
Theriogenology. 2010 Jul1;74(1):135-45. Epub 2010 Mar 7. PubMed PMID:20211487.

2009年

Miki Y, Teramura T, Tomiyama T, Onodera Y, Matsuoka T, Fukuda K, Hamanishi C.
Hyaluronan reversed proteoglycan synthesis inhibited by mechanical stress: possible involvement of antioxidant effect.
Inflamm Res. 2010 Jun;59(6):471-7. Epub 2009 Dec 15. PubMed PMID: 20013025.


Zushi S, Akagi M, Kishimoto H, Teramura T, Sawamura T, Hamanishi C.
Induction of bovine articular chondrocyte senescence with oxidized low-density lipoprotein through lectin-like oxidized low-density lipoprotein receptor 1.
Arthritis Rheum. 2009 Oct;60(10):3007-16. PubMed PMID:19790061.


Takehara T, Teramura T, Onodera Y, Kishigami S, Matsumoto K, Saeki K, Fukuda K, Hosoi Y.
Potential existence of stem cells with multiple differentiation abilities to three different germ lineages in mouse neurospheres.
Stem Cells Dev. 2009 Dec;18(10):1433-40. PubMed PMID: 19601713.


Teramura T, Onodera Y, Murakami H, Ito S, Mihara T, Takehara T, Kato H, Mitani T, Anzai M, Matsumoto K, Saeki K, Fukuda K, Sagawa N, Hosoi Y.
Mouse androgenetic embryonic stem cells differentiated to multiple cell lineages in three embryonic germ layers in vitro.
J Reprod Dev. 2009 Jun;55(3):283-92. Epub 2009 Mar 19. PubMed PMID: 19305126.


2008年

Takehara T, Teramura T, Onodera Y, Kakegawa R, Fukunaga N, Takenoshita M, Sagawa N, Fukuda K, Hosoi Y.
Rho-associated kinase inhibitor Y-27632 promotes survival of cynomolgus monkey embryonic stem cells.
Mol Hum Reprod. 2008 Nov;14(11):627-34. Epub 2008 Oct 21. PubMed PMID: 18940855; PubMed Central PMCID:PMC2639404.


Kakegawa R, Teramura T, Takehara T, Anzai M, Mitani T, Matsumoto K, Saeki K, Sagawa N, Fukuda K, Hosoi Y.
Isolation and culture of rabbit primordial germ cells.
J Reprod Dev. 2008 Oct;54(5):352-7. Epub 2008 Jul 16. PubMed PMID:18628591.


Teramura T, Fukuda K, Kurashimo S, Hosoi Y, Miki Y, Asada S, Hamanishi C.
Isolation and characterization of side population stem cells in articular synovial tissue.
BMC Musculoskelet Disord. 2008 Jun 12;9:86. PubMed PMID:18549504; PubMed Central PMCID: PMC2440379.




2007年(部門開設)

Teramura T, Takehara T, Kishi N, Mihara T, Kawata N, Takeuchi H, Takenoshita M, Matsumoto K, Saeki K, Iritani A, Sagawa N, Hosoi Y.
A mouse and embryonic stem cell derived from a single embryo.
Cloning Stem Cells. 2007 Winter;9(4):485-94. PubMed PMID:18154510.


Teramura T, Takehara T, Kawata N, Fujinami N, Mitani T, Takenoshita M, Matsumoto K, Saeki K, Iritani A, Sagawa N, Hosoi Y.
Primate embryonic stem cells proceed to early gametogenesis in vitro.
Cloning Stem Cells. 2007 Summer;9(2):144-56. PubMed PMID: 17579549.


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TEL. 072-366-0221 内線(2624) FAX. 072-366-8808
e-mail. reg-med@med.kindai.ac.jp
近畿大学 高度先端総合医療センター 再生医療部


近畿大学
高度先端総合医療センター
再生医療部

〒589-8511
大阪府大阪狭山市大野東377-2

TEL 072-366-0221 内線(2624)
FAX 072-366-8808