RESEARCH研究

2018 研究業績・論文発表

論文

Y. Kobayashi, C. Ambrogio and T. Mitsudomi

Ground-glass nodules of the lung in never-smokers and smokers: clinical and genetic insights

Transl Lung Cancer Res (2018) 7: 487-497.

Y. Kobayashi, T. Fujino, M. Nishino, T. Koga, M. Chiba, Y. Sesumi, S. Ohara, M. Shimoji, K. Tomizawa, T. Takemoto and T. Mitsudomi

EGFR T790M and C797S Mutations as Mechanisms of Acquired Resistance to Dacomitinib

J Thorac Oncol (2018) 13: 727-731.

T. Koga, Y. Kobayashi, K. Tomizawa, K. Suda, T. Kosaka, Y. Sesumi, T. Fujino, M. Nishino, S. Ohara, M. Chiba, M. Shimoji, T. Takemoto, M. Suzuki, P. A. Janne and T. Mitsudomi

Activity of a novel HER2 inhibitor, poziotinib, for HER2 exon 20 mutations in lung cancer and mechanism of acquired resistance: An in vitro study

Lung Cancer (2018) 126: 72-79.

M. Nishino, K. Suda, Y. Kobayashi, S. Ohara, T. Fujino, T. Koga, M. Chiba, M. Shimoji, K. Tomizawa, T. Takemoto and T. Mitsudomi

Effects of secondary EGFR mutations on resistance against upfront osimertinib in cells with EGFR-activating mutations in vitro

Lung Cancer (2018) 126: 149-155.

M. Nishio, K. Nakagawa, T. Mitsudomi, N. Yamamoto, T. Tanaka, H. Kuriki, A. Zeaiter and T. Tamura

Analysis of central nervous system efficacy in the J-ALEX study of alectinib versus crizotinib in ALK-positive non-small-cell lung cancer

Lung Cancer (2018) 121: 37-40.

K. Suda, J. Kim, I. Murakami, L. Rozeboom, M. Shimoji, S. Shimizu, C. J. Rivard, T. Mitsudomi, A. C. Tan and F. R. Hirsch

Innate Genetic Evolution of Lung Cancers and Spatial Heterogeneity: Analysis of Treatment-Naive Lesions

J Thorac Oncol (2018) 13: 1496-1507.

K. Suda, I. Murakami, H. Yu, J. Kim, A. C. Tan, H. Mizuuchi, L. Rozeboom, K. Ellison, C. J. Rivard, T. Mitsudomi and F. R. Hirsch

CD44 Facilitates Epithelial-to-Mesenchymal Transition Phenotypic Change at Acquisition of Resistance to EGFR Kinase Inhibitors in Lung Cancer

Mol Cancer Ther (2018) 17: 2257-2265.