研究
Hajime Honjo, Tomohiro Watanabe, Yasuo Otsuka, Yasuhiro Masuta, Sho Masaki, Ken Kamata, Kosuke Minaga, Seiichi Omura, Ah-Mee Park, Masatoshi Kudo
Nucleotide-binding oligomerization domain 2-independent colonization by Turicimonas muris induced by high-fat diet protects against dextran sodium sulfate-induced colitis.
Clinical and experimental immunology 2026年9月12日
Masatoshi Kudo, Ghassan K Abou-Alfa, Zhenggang Ren, Jeong Heo, Riccardo Lencioni, Yasuaki Arai, Mohamed Bouattour, Maria A Gonzalez-Carmona, Yabing Guo, Ai-Bing Xu …
Durvalumab and tremelimumab, with or without lenvatinib, combined with transarterial chemoembolisation in participants with embolisation-eligible hepatocellular carcinoma (EMERALD-3): a global, randomised, open-label, sponsor-blinded, phase 3 study.
The Lancet. Oncology 27(9) 1077-1093 2026年9月
Kosuke Minaga, Masatoshi Kudo
Toward Global Harmonization of EUS-Guided Biliary Drainage: A Step Beyond Regional Consensus.
Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society 38(9) e70275 2026年9月
Masatoshi Kudo, Sadahisa Ogasawara, Ruibao Liu, Shanzhi Gu, Kunyuan Wang, Ming Zhao, Hongtao Hu, Zhaoyu Liu, Kecan Lin, Jingfeng Liu …
On-demand transarterial chemoembolisation combined with atezolizumab and bevacizumab in patients with untreated hepatocellular carcinoma (TALENTACE): a multicentre, randomised, open-label, phase 3 trial.
The lancet. Gastroenterology & hepatology 2026年8月25日
Tomohiro Watanabe, Masatoshi Kudo
Multiple Modes of Action of Anti-TNF-α Antibodies for Inflammatory Bowel Diseases Beyond TNF-α Neutralization.
Antibodies (Basel, Switzerland) 15(4) 2026年8月6日
Emi Tanaka, Toshifumi Tada, Atsushi Hiraoka, Masashi Hirooka, Kazuya Kariyama, Joji Tani, Masanori Atsukawa, Koichi Takaguchi, Ei Itobayashi, Takashi Nishimura …
Usefulness of the Lymphocyte-to-Monocyte Ratio in Predicting Prognosis in Patients with Hepatocellular Carcinoma Receiving Atezolizumab Plus Bevacizumab.
Oncology 1-26 2026年8月3日
Kazunari Tanaka, Kunihiko Tsuji, Atsushi Hiraoka, Toshifumi Tada, Masashi Hirooka, Kazuya Kariyama, Joji Tani, Masanori Atsukawa, Koichi Takaguchi, Ei Itobayashi …
Baseline DCP May Modify Response to Atezolizumab-Bevacizumab Versus Durvalumab-Tremelimumab in Unresectable HCC.
Liver international : official journal of the International Association for the Study of the Liver 46(8) e70803 2026年8月
Atsushi Hiraoka, Toshifumi Tada, Masashi Hirooka, Kazuya Kariyama, Joji Tani, Masanori Atsukawa, Koichi Takaguchi, Ei Itobayashi, Takashi Nishimura, Kunihiko Tsuji …
Simplified BALAD (BALAD-S) Score as a Guide for First-Line Immune Checkpoint Inhibitor Selection for Unresectable Hepatocellular Carcinoma.
Hepatology research : the official journal of the Japan Society of Hepatology 2026年7月16日
Alessandro Vitale, Gordon Guyatt, Masatoshi Kudo, Laura Kulik, David J Pinato, Laura Crocetti, Edoardo G Giannini, Umberto Cillo
Personalised decision-making in hepatocellular carcinoma: conceptual evolution over two decades.
BJS open 10(4) 2026年7月3日
Yasuo Otsuka, Tomohiro Watanabe, Masatoshi Kudo
A novel cancer gene therapy achieving reciprocal regulation of PTEN and PARP1 expression.
Molecular therapy. Oncology 34(2) 201194-201194 2026年6月18日
Pei-Chang Lee, Alessio Cortellini, Bernardo Stefanini, Changhoon Yoo, Hong Jae Chon, Jaekyung Cheon, Masatoshi Kudo, Naoshi Nishida, Bernhard Scheiner, Matthias Pinter …
Determinants of long-term survival from atezolizumab plus bevacizumab in unresectable hepatocellular carcinoma.
European journal of cancer (Oxford, England : 1990) 240 116749-116749 2026年6月3日
Andrea Casadei-Gardini, Terry Cheuk-Fung Yip, Alessandro Vitale, Federico Rossari, Toshifumi Tada, Goki Suda, Shigeo Shimose, Masatoshi Kudo, Jaekyung Cheon, Fabian Finkelmeier …
Early and late survival dynamics of immunotherapy combinations in advanced HCC: Anchored indirect comparison of atezolizumab plus bevacizumab versus durvalumab + tremelimumab.
European journal of cancer (Oxford, England : 1990) 240 116750-116750 2026年6月3日
Keisuke Koroki, Masaru Wakatsuki, Sadahisa Ogasawara, Hirokazu Makishima, Taro Watabe, Haruka Anzai, Makoto Fujiya, Midori Sawada, Takahiro Tsuchiya, Keiichi Katayama …
Phase Ib/II trial to evaluate the safety and efficacy of atezolizumab and bevacizumab as adjuvant therapy following carbon-ion radiotherapy in hepatocellular carcinoma (VANGUARD): study protocol.
BMJ open 16(6) e115731 2026年6月2日
Shunsuke Omoto, Mamoru Takenaka, Akane Hara, Yasuo Otsuka, Akihiro Yoshida, Kosuke Minaga, Masatoshi Kudo
Half-release and full aspiration technique for endoscopic ultrasound-guided hepaticogastrostomy in severe acute cholangitis.
Endoscopy 58(S 02) E613-E614 2026年6月
Kosuke Minaga, Masatoshi Kudo
Beyond Equivalence: Reconsidering the Role of EUS-Guided Gallbladder Drainage in the Post-ERCP Failure Algorithm.
Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society 38(6) e70191 2026年6月
Tomomitsu Matono, Toshifumi Tada, Atsushi Hiraoka, Masashi Hirooka, Yoshiko Nakamura, Osamu Yoshida, Kazuya Kariyama, Kazuhiro Nouso, Joji Tani, Asahiro Morishita …
Outcomes of Patients With Hepatocellular Carcinoma Treated With Durvalumab Plus Tremelimumab in Real-World Clinical Practice Who Met or Did Not Meet the Inclusion Criteria for the Phase 3 HIMALAYA Trial.
Journal of gastroenterology and hepatology 2026年5月22日
Kazuya Kariyama, Kazuhiro Nouso, Atsushi Hiraoka, Fujimasa Tada, Hideko Ohama, Hidenori Toyoda, Satoshi Yasuda, Toshifumi Tada, Kazunari Tanaka, Kunihiko Tsuji …
Ablation-Based Salvage Strategy at Disease Progression After Initial Disease Control With Atezolizumab/Bevacizumab in Hepatocellular Carcinoma.
Hepatology research : the official journal of the Japan Society of Hepatology 2026年5月11日
Kaho Aoe, Toshifumi Tada, Atsushi Hiraoka, Tomomitsu Matono, Masashi Hirooka, Kazuya Kariyama, Joji Tani, Masanori Atsukawa, Koichi Takaguchi, Ei Itobayashi …
Optimizing bevacizumab exposure in atezolizumab-based therapy for unresectable hepatocellular carcinoma: A nationwide real-world study.
Hepatology (Baltimore, Md.) 2026年5月6日
Saki Yoshida, Yoriaki Komeda, Masashi Kono, Kohei Handa, Tomoyuki Nagai, Satoru Hagiwara, Shunsuke Omoto, Mamoru Takenaka, Hiroshi Kashida, George Tribonias …
Diagnostic Utility of Endoscopic Features and Endoscopic Ultrasonography for Ulcerative Colitis-Associated Neoplasia: A Retrospective Study on the Role of Endoscopic Submucosal Dissection as a Total Biopsy.
Cancers 18(9) 2026年5月6日
Lorenza Rimassa, Stephen L Chan, Bruno Sangro, George Lau, Masatoshi Kudo, Maria Reig, Valeriy Breder, Min-Hee Ryu, Yurii Ostapenko, Wattana Sukeepaisarnjaroen …
Plain language summary of five-year overall survival update from the HIMALAYA study of tremelimumab plus durvalumab in unresectable hepatocellular carcinoma (liver cancer).
Future oncology (London, England) 22(12) 1359-1372 2026年5月
Fujimasa Tada, Atsushi Hiraoka, Hideko Ohama, Toshifumi Tada, Masashi Hirooka, Kazuya Kariyama, Joji Tani, Masanori Atsukawa, Koichi Takaguchi, Ei Itobayashi …
Clinical Characteristics, Predictive Factors, and the Impact of Antithrombotic Therapy on Bleeding Events in Unresectable Hepatocellular Carcinoma Treated With Atezolizumab Plus Bevacizumab.
Hepatology research : the official journal of the Japan Society of Hepatology 2026年4月21日
David T Fetzer, Yuko Kono, Fabio Piscaglia, Christoph F Dietrich, Franca Meloni, Qiang Lu, Dirk-Andre Clevert, Andrej Lyshchik, Yasunori Minami, Jeong Min Lee …
Contrast-enhanced ultrasound LI-RADS nonradiation treatment response assessment: applications, challenges, and future directions.
Abdominal radiology (New York) 2026年4月10日
Thomas Yau, Peter R Galle, Thomas Decaens, Bruno Sangro, Shukui Qin, Leonardo G da Fonseca, Hatim Karachiwala, Jean-Frederic Blanc, Joong-Won Park, Edward Gane …
A plain language summary of the CheckMate 9DW study: nivolumab in combination with ipilimumab for unresectable hepatocellular carcinoma (advanced liver cancer).
Future oncology (London, England) 22(10) 1135-1152 2026年4月
Masatoshi Kudo
Sequential ICI plus Anti-VEGF/TKI with On-Demand TACE beyond RECIST Progression Improves Pathological Response, Resectability, and Survival in Unresectable HCC.
Liver cancer 15(2) 169-177 2026年4月
Masashi Kono, Yoriaki Komeda, Hiroshi Kashida, Satoru Hagiwara, Akihiro Yoshida, Shunsuke Omoto, Mamoru Takenaka, Naoko Tsuji, George Tribonias, Masatoshi Kudo
A Case of Human Epidermal Growth Factor Receptor 2-Positive Colon Cancer With Invasive Micropapillary Carcinoma Component.
DEN open 6(1) e70184 2026年4月
Jung Sun Kim, San-Chi Chen, Jeffrey Sum Lung Wong, Beodeul Kang, Ho Yeong Lim, Ilhwan Kim, Hyeyeong Kim, Chansik An, Su Jin Jang, Masatoshi Kudo …
Efficacy of Nivolumab plus Ipilimumab in Advanced Hepatocellular Carcinoma with and without High-Risk Features: An International Multicenter Study.
Liver cancer 2026年3月23日
Takeshi Terashima, Masafumi Ikeda, Taro Yamashita, Takuji Okusaka, Hiroshi Imaoka, Tomokazu Kawaoka, Satoshi Kobayashi, Sadahisa Ogasawara, Atsushi Hiraoka, Masahito Nakano …
A Multicenter Phase II Study on Atezolizumab plus Bevacizumab Combination Therapy in Patients with Unresectable Hepatocellular Carcinoma and Child-Pugh Classification B Cirrhosis: CHALLENGE Trial.
Liver cancer 2026年3月12日
Tomoko Aoki, Masatoshi Kudo, Satoshi Ogiso, Genki Okumura, Megumi Hoshino, Yuka Nakamura, Ryo Morisue, Shohei Koyama, Naoshi Nishida, Kohei Hanaoka …
Clinical Prediction of Glycolysis-Driven Molecular Subclass of Hepatocellular Carcinoma without Transcriptomic Profiling.
Liver cancer 2026年3月5日
Amit Mahipal, Ann-Lii Cheng, Masatoshi Kudo, Adam Burgoyne, Aparna Kalyan, Riccardo Lencioni, Carlos Lopéz Lopéz, Bruno Daniele, Daniel H Palmer, Ari David Baron …
Characterization of Patients with Unresectable Hepatocellular Carcinoma in REFLECT Who Achieved Tumor Response or Alpha-Fetoprotein Response When Treated with Lenvatinib.
Liver cancer 2026年3月5日
Jung Sun Kim, Jeffrey Wong, San-Chi Chen, David Tai, Hannah Yang, Youngun Kim, Beodeul Kang, Ilhwan Kim, Hyeyeong Kim, Chansik An …
Outcomes of Nivolumab Plus Ipilimumab After Atezolizumab Plus Bevacizumab in Advanced HCC: An International Multicentre Study.
Liver international : official journal of the International Association for the Study of the Liver 46(2) e70493 2026年2月
Hideko Ohama, Atsushi Hiraoka, Toshifumi Tada, Masashi Hirooka, Kazuya Kariyama, Joji Tani, Masanori Atsukawa, Koichi Takaguchi, Ei Itobayashi, Shinya Fukunishi …
Efficacy and Safety of Atezolizumab Plus Bevacizumab Versus Durvalumab Plus Tremelimumab for Unresectable Hepatocellular Carcinoma in Patients With Child-Pugh Class B: A Real-World Study.
Hepatology research : the official journal of the Japan Society of Hepatology 2026年1月9日
Daisuke Fujihara, Hajime Honjo, Yasuhiro Masuta, Yasuo Otsuka, Sho Masaki, Kosuke Minaga, Ken Kamata, Naoko Tsuji, Tomohiro Watanabe, Masatoshi Kudo
Enhanced mRNA Expression of Colonic IL-6 in Cronkhite-Canada Syndrome Bearing Colorectal Cancer.
In vivo (Athens, Greece) 40(3) 1810-1817 2026年
Yasuo Otsuka, Kosuke Minaga, Akane Hara, Mamoru Takenaka, Chihoko Nobori, Takaaki Murase, Ippei Matsumoto, Masatoshi Kudo
A Rare but Life-Threatening Complication of Direct Endoscopic Necrosectomy: Tension Pneumoperitoneum With Pneumothorax and Hypercapnia due to Walled-Off Necrosis Rupture.
Case reports in gastrointestinal medicine 2026 6599334-6599334 2026年
Tomoko Aoki, Masakatsu Tsurusaki, Naoshi Nishida, Masahiro Morita, Hirokazu Chishina, Masahiro Takita, Satoru Hagiwara, Yasunori Minami, Kazuomi Ueshima, Masatoshi Kudo
Double-balloon (CANDIS) Retrograde Transvenous Obliteration Improves Hepatic Functional Reserve Compared with the Conventional Method.
Interventional radiology (Higashimatsuyama-shi (Japan) 11 e20250101 2026年
Tomoyuki Nagai, Yoriaki Komeda, Saki Yoshida, Kohei Handa, Sho Masaki, Masashi Kono, Hajime Honjo, Shigenaga Matsui, Naoko Tsuji, Hiroshi Kashida …
Caloric Restriction Is Associated With Enhanced Clinical Outcomes in Hospitalized Patients With Ulcerative Colitis.
Gastro hep advances 5(2) 100842-100842 2026年