研究

Ikeda M, Yamashita T, Ogasawara S, Kudo M

Multicenter Phase II trial of lenvatinib plus hepatic intra-arterial infusion chemotherapy with cisplatin for advanced hepatocellular carcinoma: LEOPARD

Omoto S, Takenaka M, Fukunaga T, Takashima K, Komeda Y, Jeong S, Kudo M

The "echo-free space" technique: a safe and reliable method for endoscopic ultrasound scope insertion.

Omoto S, Takenaka M, Fukunaga T, Okamoto A, Komeda Y, Jeong S, Kudo M

Diagnosis of an intraductal papillary neoplasm of the bile duct with fibrovascular stalks using detective flow imaging

Otsuka Y, Hara A, Minaga K, Sekai I, Kurimoto M, Masuta Y, Takada R, Yoshikawa T, Kamata K, Kudo M

Leucine-rich repeat kinase 2 promotes the development of experimental severe acute pancreatitis.

Bachir Taouli, Ahmed Ba-Ssalamah, Julius Chapiro, Jagpreet Chhatwal, Kathryn Fowler, Tae Wook Kang, Gesine Knobloch, Dow-Mu Koh, Masatoshi Kudo, Jeong Min Lee …

Correction to: Consensus report from the 10th Global Forum for Liver Magnetic Resonance Imaging: developments in HCC management.

Arndt Vogel, Richard S Finn, Marie-Hélène Blanchet Zumofen, Carolina Heuser, Javier Sanchez Alvarez, Michael Leibfried, Catherine R Mitchell, Sarah Batson, Gabrielle Redhead, Vincent E Gaillard …

Atezolizumab in Combination with Bevacizumab for the Management of Patients with Hepatocellular Carcinoma in the First-Line Setting: Systematic Literature Review and Meta-Analysis.

Kamata K, Takenaka M, Nishida N, Hara A, Otsuka Y, Tanaka H, Omoto S, Minaga K, Yamao K, Chiba Y, Sakai K, Nishio K, Watanabe T, Kudo M

Impact of Smad4 and p53 mutations on the prognosis of patients with pancreatic ductal adenocarcinoma undergoing chemotherapy.

Takenaka M, Lee TH, Kudo M

Glove box method: Simple and effective right-hand free method for interventional endoscopy.

Qin S†, Chen M†, Cheng AL†, Kaseb AO†, Kudo M

Atezolizumab plus bevacizumab versus active surveillance in patients with resected or ablated high-risk hepatocellular carcinoma (IMbrave050): a randomised, open-label, multicentre, phase 3 trial.

Abou-Alfa GK†, Lau G†, Kudo M

Plain language summary of results from the HIMALAYA study: tremelimumab and durvalumab for the treatment of participants with unresectable hepatocellular carcinoma (liver cancer).

Sugimori H, Masaki S, Honjo H, Kudo M

Visualization of gastrointestinal bezoar movement causing and releasing small bowel obstruction on computed tomography in a patient with diabetes mellitus.

Hatanaka T, Kariyama K, Tani J, Atsukawa M, Takaguchi K, Itobayashi E, Fukunishi S, Tsuji K, Ishikawa T, Tajiri K, Ochi H, Yasuda S, Toyoda H, Ogawa C, Yokohama K, Nishikawa H, Nishimura T, Shimada N, Kawata K, Kosaka H, Naganuma A, Yata Y, Ohama H, Kuroda H, Tanaka K, Tanaka T, Tada F, Nouso K, Morishita A, Tsutsui A, Nagano T, Itokawa N, Okubo T, Arai T, Imai M, Koizumi Y, Nakamura S, Kaibori M, Iijima H, Hiasa Y, Kudo M

Comparing the impact of atezolizumab plus bevacizumab and lenvatinib on the liver function in hepatocellular carcinoma patients: A mixed-effects regression model approach

Nishida N, Kudo M

Genetic/Epigenetic alteration and tumor immune microenvironment in intrahepatic cholangiocarcinoma: Transforming the immune microenvironment with molecular-targeted agents

Kudo M

Impact of bevacizumab being skipped due to adverse events of special interest for bevacizumab in patients with unresectable hepatocellular carcinoma treated with atezolizumab plus bevacizumab: An exploratory analysis of the Phase III IMbrave150 study.

Federico Rossari, Toshifumi Tada, Goki Suda, Shigeo Shimose, Masatoshi Kudo, Changhoon Yoo, Jaekyung Cheon, Fabian Finkelmeier, Ho Yeong Lim, José Presa …

α-FAtE: A new predictive score of response to atezolizumab plus bevacizumab for unresectable hepatocellular carcinoma.

Takeshi Hatanaka, Satoru Kakizaki, Atsushi Hiraoka, Toshifumi Tada, Masashi Hirooka, Kazuya Kariyama, Joji Tani, Masanori Atsukawa, Koichi Takaguchi, Ei Itobayashi …

A comparative analysis of the therapeutic outcomes of atezolizumab plus bevacizumab and lenvatinib for hepatocellular carcinoma patients aged 80 years and older: A multicenter study.
Hepatology research : the official journal of the Japan Society of Hepatology

Ciro Celsa, Giuseppe Cabibbo, Claudia Am Fulgenzi, Bernhard Scheiner, Antonio d'Alessio, Giulia F Manfredi, Naoshi Nishida, Celina Ang, Thomas U Marron, Anwaar Saeed …

Characteristics and outcomes of immunotherapy-related liver injury in patients with hepatocellular carcinoma versus other advanced solid tumours.

Bachir Taouli, Ahmed Ba-Ssalamah, Julius Chapiro, Jagpreet Chhatwal, Kathryn Fowler, Tae Wook Kang, Gesine Knobloch, Dow-Mu Koh, Masatoshi Kudo, Jeong Min Lee …

Correction: Consensus report from the 10th global forum for liver magnetic resonance imaging: multidisciplinary team discussion.

Teerha Piratvisuth, Jinlin Hou, Tawesak Tanwandee, Thomas Berg, Arndt Vogel, Jörg Trojan, Enrico N De Toni, Masatoshi Kudo, Anja Eiblmaier, Hanns-Georg Klein …

Development and clinical validation of a novel algorithmic score (GAAD) for detecting HCC in prospective cohort studies.

Kudo M

Current therapeutic strategies for hepatocellular carcinoma in Japan.

Toshifumi Tada, Takashi Kumada, Atsushi Hiraoka, Masashi Hirooka, Kazuya Kariyama, Joji Tani, Masanori Atsukawa, Koichi Takaguchi, Ei Itobayashi, Shinya Fukunishi …

Comparison of prognostic impact of atezolizumab plus bevacizumab versus lenvatinib in patients with intermediate-stage hepatocellular carcinoma.

Masatoshi Kudo, Richard S Finn, Ann-Lii Cheng, Andrew X Zhu, Michel Ducreux, Peter R Galle, Naoya Sakamoto, Naoya Kato, Michitaka Nakano, Jing Jia …

Albumin-Bilirubin Grade Analyses of Atezolizumab plus Bevacizumab versus Sorafenib in Patients with Unresectable Hepatocellular Carcinoma: A Post Hoc Analysis of the Phase III IMbrave150 Study.

Watanabe T, Minaga K, Honjo H, Kudo M

Oral administration of ovalbumin protects mice from concanavalin A-induced hepatitis through suppression of interferon-gamma responses.

Kono M, Komeda Y, Tribonias G, Yoshida S, Nomura K, Handa K, Nagai T, Hagiwara S, Omoto S, Takenaka M, Nishida N, Tsuji N, Kashida H, Kudo M

Serum leucine-rich alpha-2 glycoprotein in monitoring disease activity and intestinal mucosal healing for biotherapy-naïve cases with ulcerative colitis.

Masuta Y, Otsuka Y, Minaga K, Honjo H, Kudo M

Regulation of type I IFN responses by deubiquitinating enzyme A in inflammatory bowel diseases.

Otsuka Y, Minaga K, Hara A, Masuta Y, Takenaka M, Kudo M

Piercing technique for mucosal hyperplasia at an uncovered part of a partially covered stent after endoscopic ultrasound-guided hepaticogastrostomy.

Kamata K, Imai H, Matsumoto H, Yamashita Y, Kato T, Nishi K, Omoto S, Minaga K, Yamao K, Hyodo T, Im SW, Hara A, Yoshikawa T, Ishikawa R, Okamoto A, Yamazaki T, Nakai A, Ueshima K, Chiba Y, Takenaka M, Watanabe T, Kitano M, Kudo M

Low‐dose gemcitabine plus nab‐paclitaxel versus standard‐dose gemcitabine plus nab‐paclitaxel in elderly patients with metastatic pancreatic cancer: A randomized Phase II trial

Minami Y, Aoki T, Hagiwara S, Kudo M

Tips for preparing and practicing thermal ablation therapy of hepatocellular carcinoma.

Fujita S, Honjo H, Takada R, Hara A, Masuta Y, Otsuka Y, Handa K, Minaga K, Tsuji S, Kudo M

Ulcerative Colitis-associated Spondyloarthritis Successfully Treated with Infliximab in the Absence of Enhanced TNF-α Responses

Philippe Merle, Masatoshi Kudo, Julien Edeline, Mohamed Bouattour, Ann-Lii Cheng, Stephen L Chan, Thomas Yau, Marcelo Garrido, Jennifer Knox, Bruno Daniele …

Pembrolizumab as Second-Line Therapy for Advanced Hepatocellular Carcinoma: Longer Term Follow-Up from the Phase 3 KEYNOTE-240 Trial.

Kudo M

All stages of hepatocellular carcinoma patients benefit from systemic therapy combined with locoregional therapy.

Laurent Peyrin-Biroulet, Jessica R Allegretti, David T Rubin, Brian Bressler, Matthew Germinaro, Kuan-Hsiang Gary Huang, Nicole Shipitofsky, Hongyan Zhang, Rebbecca Wilson, Chenglong Han …

Guselkumab in Patients With Moderately to Severely Active Ulcerative Colitis: QUASAR Phase 2b Induction Study.

Enrui Xie, Yee Hui Yeo, Bernhard Scheiner, Yue Zhang, Atsushi Hiraoka, Xinxing Tantai, Petros Fessas, Tiago de Castro, Antonio D'Alessio, Claudia Angela Maria Fulgenzi …

Immune Checkpoint Inhibitors for Child-Pugh Class B Advanced Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis.

Hiroko Iijima, Masatoshi Kudo, Shoji Kubo, Masayuki Kurosaki, Michiie Sakamoto, Shuichiro Shiina, Ryosuke Tateishi, Osamu Nakashima, Takumi Fukumoto, Yutaka Matsuyama …

Report of the 23rd Nationwide Follow-Up Survey of Primary Liver Cancer in Japan (2014-2015).

Masatoshi Kudo, Richard S Finn, Peter R Galle, Andrew X Zhu, Michel Ducreux, Ann-Lii Cheng, Masafumi Ikeda, Kaoru Tsuchiya, Ken-Ichi Aoki, Jing Jia …

IMbrave150: Efficacy and Safety of Atezolizumab plus Bevacizumab versus Sorafenib in Patients with Barcelona Clinic Liver Cancer Stage B Unresectable Hepatocellular Carcinoma: An Exploratory Analysis of the Phase III Study.

Masuta Y, Minaga K, Otsuka Y, Takenaka M, Kudo M

Usefulness of detective flow imaging endoscopic ultrasound for the diagnosis of rectal wall thickening.

Kudo M

Drug-off criteria in patients with hepatocellular carcinoma who achieved clinical complete response after combination treatment with immunotherapy and locoregional therapy.

Bachir Taouli, Ahmed Ba-Ssalamah, Julius Chapiro, Jagpreet Chhatwal, Kathryn Fowler, Tae Wook Kang, Gesine Knobloch, Dow-Mu Koh, Masatoshi Kudo, Jeong Min Lee …

Consensus report from the 10th global forum for liver magnetic resonance imaging: multidisciplinary team discussion.

Kudo M

A Phase 2, prospective, multicenter, single-arm trial of transarterial chemoembolization therapy in combination strategy with lenvatinib in patients with unresectable Intermediate-stage hepatocellular carcinoma: TACTICS-L trial.

Kudo M

Adjuvant atezolizumab-bevacizumab after curative therapy for hepatocellular carcinoma.

Kato H, Hagiwara S, Nishida N, Komeda Y, Yoshida A, Kudo M

A case of transcatheter arterial embolization for intraperitoneal hemorrhage due to gaint hepatic segmental arterial mediolysis

Philippe Merle, Masatoshi Kudo, Stanimira Krotneva, Kirhan Ozgurdal, Yun Su, Irina Proskorovsky

Regorafenib versus Cabozantinib as a Second-Line Treatment for Advanced Hepatocellular Carcinoma: An Anchored Matching-Adjusted Indirect Comparison of Efficacy and Safety.

Masatoshi Kudo

Surveillance, Diagnosis, and Treatment Outcome of Hepatocellular Carcinoma in Japan: 2023 Update.

Honjo H, Masuta Y, Otsuka Y, Masaki S, Minaga K, Kudo M

Analyses of cytokine gene expression and fecal microbiota in a patient with Cronkhite-Canada syndrome successfully treated with prednisolone

Minami Y, Nishida N, Kudo M

Imaging diagnosis of various hepatocellular carcinoma subtypes and its hypervascular mimics: Differential diagnosis based on conventional interpretation and artificial intelligence.

Kamata K, Hara A, Minaga K, Yoshikawa T, Kurimoto M, Sekai I, Okai N, Omaru N, Masuta Y, Otsuka Y, Takada R, Takamura S, Kudo M

Activation of the aryl hydrocarbon receptor inhibits the development of experimental autoimmune pancreatitis through IL-22-mediated signaling pathways.

Kudo M

Adjuvant atezolizumab-bevacizumab after resection or ablation for hepatocellular carcinoma

Bruno Sangro, Thomas Yau, Anthony B El-Khoueiry, Masatoshi Kudo, Yun Shen, Marina Tschaika, Amit Roy, Yan Feng, Ling Gao, Urvi Aras

Exposure-response analysis for nivolumab plus ipilimumab combination therapy in patients with advanced hepatocellular carcinoma (CheckMate 040).

Nishida N, Aoki T, Morita M, Chishina H, Takita M, Ida H, Hagiwara S, Minami Y, Ueshima K, Kudo M

Non-inflamed tumor microenvironment and methylation/downregulation of antigen-presenting machineries in cholangiocarcinoma.

Morita M, Nishida N, Aoki T, Chishina H, Takita M, Ida H, Hagiwara S, Minami Y, Ueshima K, Kudo M

Role of β-catenin activation in the tumor immune microenvironment and immunotherapy of hepatocellular carcinoma

Kudo M

The Society for Immunotherapy of Cancer clinical practice guideline on immunotherapy for hepatocellular carcinoma.

Mara Persano, Margherita Rimini, Toshifumi Tada, Goki Suda, Shigeo Shimose, Masatoshi Kudo, Jaekyung Cheon, Fabian Finkelmeier, Ho Yeong Lim, José Presa …

Identification of Atezolizumab Plus Bevacizumab Prognostic Index via Recursive Partitioning Analysis in HCC: The ABE Index.

Mathew Vithayathil, Antonio D'Alessio, Claudia Angela Maria Fulgenzi, Naoshi Nishida, Martin Schönlein, Johann von Felden, Kornelius Schulze, Henning Wege, Anwaar Saeed, Brooke Wietharn…

Impact of body mass index in patients receiving atezolizumab plus bevacizumab for hepatocellular carcinoma.

Margherita Rimini, Mara Persano, Toshifumi Tada, Goki Suda, Shigeo Shimose, Masatoshi Kudo, Jaekyung Cheon, Fabian Finkelmeier, Ho Yeong Lim, José Presa …

Real-World Data for Atezolizumab Plus Bevacizumab in Unresectable Hepatocellular Carcinoma: How Does Adherence to the IMbrave150 Trial Inclusion Criteria Impact Prognosis?

Yasuo Otsuka, Ken Kamata, Masatoshi Kudo

Contrast-Enhanced Harmonic Endoscopic Ultrasound-Guided Puncture for the Patients with Pancreatic Masses.

Yasuo Otsuka, Yoriaki Komeda, Masayuki Takeda, Takayuki Takahama, Masashi Kono, Mamoru Takenaka, Satoru Hagiwara, Naoshi Nishida, Hiroshi Kashida, Masatoshi Kudo

Long-Term Survival of More than 5 Years with Maintenance Therapy Using Single-Agent Pemetrexed in a Patient with Diffuse Malignant Peritoneal Mesothelioma

Kiyoshi Hasegawa, Nobuyuki Takemura, Tatsuya Yamashita, Takeyuki Watadani, Masaki Kaibori, Shoji Kubo, Mitsuo Shimada, Hiroaki Nagano, Etsuro Hatano, Hiroshi Aikata, Hiroko Iijima, Kazuomi Ueshima, Kazuyoshi Ohkawa, Takuya Genda, Kaoru Tsuchiya, Takuji Torimura, Masafumi Ikeda, Junji Furuse, Masaaki Akahane, Satoshi Kobayashi, Hideyuki Sakurai, Atsuya Takeda, Takamichi Murakami, Utaroh Motosugi, Yutaka Matsuyama, Masatoshi Kudo, Ryosuke Tateishi

Clinical Practice Guidelines for Hepatocellular Carcinoma: The Japan Society of Hepatology 2021 Version (5th JSH-HCC Guidelines).

Amit G Singal, Masatoshi Kudo, Jordi Bruix

Breakthroughs in hepatocellular carcinoma therapies.

Margherita Rimini, Mara Persano, Toshifumi Tada, Goki Suda, Shigeo Shimose, Masatoshi Kudo, Jaekyung Cheon, Fabian Finkelmeier, Ho Yeong Lim, José Presa Ramos, Gianluca Masi, Changhoon Yoo, Sara Lonardi, Bernardo Stefanini, Takashi Kumada, Naoya Sakamoto, Hideki Iwamoto, Tomoko Aoki, Hong Jae Chon, Vera Himmelsbach, Margarida Montes, Caterina Vivaldi, Caterina Soldà, Atsushi Hiraoka, Takuya Sho, Takashi Niizeki, Naoshi Nishida, Christoph Steup, Masashi Hirooka, Kazuya Kariyama, Joji Tani, Masanori Atsukawa, Koichi Takaguchi, Ei Itobayashi, Shinya Fukunishi, Kunihiko Tsuji, Toru Ishikawa, Kazuto Tajiri, Hironori Ochi, Satoshi Yasuda, Hidenori Toyoda, Chikara Ogawa, Takashi Nishimura, Takeshi Hatanaka, Satoru Kakizaki, Noritomo Shimada, Kazuhito Kawata, Fujimasa Tada, Hideko Ohama, Kazuhiro Nouso, Asahiro Morishita, Akemi Tsutsui, Takuya Nagano, Norio Itokawa, Tomomi Okubo, Taeang Arai, Michitaka Imai, Hisashi Kosaka, Atsushi Naganuma, Yohei Koizumi, Shinichiro Nakamura, Masaki Kaibori, Hiroko Iijima, Yoichi Hiasa, Valentina Burgio, Angelo Della Corte, Francesca Ratti, Francesco De Cobelli, Luca Aldrighetti, Mario Scartozzi, Stefano Cascinu, Andrea Casadei-Gardini

Role of the prognostic nutritional index in predicting survival in advanced hepatocellular carcinoma treated with atezolizumab plus bevacizumab.

Daizen Hirata, Hiroshi Kashida, Tsuguhiro Matsumoto, Chikara Ebisutani, Akira Teramoto, Mineo Iwatate, Santa Hattori, Mikio Fujita, Wataru Sano, Yoriaki Komeda, Yasushi Sano, Yoshitaka Murakami, Masatoshi Kudo

A Multicenter Prospective Validation Study on Selective Endoscopic Resection of Sessile Serrated Lesions Using Magnifying Colonoscopy in Clinical Practice

Naoya Kato, Masatoshi Kudo, Kaoru Tsuchiya, Atsushi Hagihara, Kazushi Numata, Hiroshi Aikata, Yoshitaka Inaba, Shunsuke Kondo, Kenta Motomura, Naohiro Okano, Masafumi Ikeda, Manabu Morimoto, Shingo Kuroda, Akiko Kimura

Cabozantinib in Japanese patients with advanced hepatocellular carcinoma: Final results of a multicenter phase 2 study.

Junji Furuse, Namiki Izumi, Kenta Motomura, Yoshitaka Inaba, Yoshio Katamura, Yasuteru Kondo, Kazuhisa Yabushita, Katsuaki Motoyoshi, Masatoshi Kudo

Safety and Effectiveness of Lenvatinib in Patients with Unresectable Hepatocellular Carcinoma in Real-World Clinical Practice: An Observational Post-Marketing Study in Japan.

Yoriaki Komeda, Masashi Kono, Hiroshi Kashida, George Tribonias, Sho Masaki, Ryutaro Takada, Tomoyuki Nagai, Satoru Hagiwara, Naoshi Nishida, Mamoru Takenaka, Hajime Honjo, Shigenaga Matsui, Naoko Tsuji, Masatoshi Kudo

Successful initial tofacitinib treatment for acute severe ulcerative colitis with steroid resistance: a case series.