主任教授　前田 法一　（まえだ　のりかず）

■医学博士

	1995年大阪大学医学部 卒業 1995年大阪大学医学部附属病院 内科研修医（第二内科） 1996年医療法人川崎病院 内科・循環器科 医員 1999年大阪大学大学院医学系研究科博士課程（生体制御医学専攻）大学院生 2003年医学博士の学位授与（大阪大学） 2003年大阪大学大学院医学系研究科 分子制御内科学教室 研究生 2004年日本学術振興会特別研究員(PD) 大阪大学大学院医学系研究科 分子制御内科学教室 2006年大阪大学大学院医学系研究科 内分泌・代謝内科学 特任研究員 2009年同 助教 2011年同 医学部講師 2016年大阪大学大学院医学系研究科 代謝血管学寄附講座 寄附講座准教授 2016年（兼）大阪大学医学部附属病院 糖尿病・内分泌・代謝内科 外来医長 2018年（兼）大阪大学医学部附属病院 糖尿病センター 副センター長 2019年（兼）大阪大学医学部附属病院 内科系外来医長・師長会議 代表 2020年大阪大学医学部附属病院 糖尿病・内分泌・代謝内科 診療局長 2022年 （兼）大阪大学医学部附属病院 診療局長等連絡会議 代表 2023年近畿大学 主任教授（内分泌・代謝・糖尿病内科） 現在に至る
	日本内科学会 認定内科医 日本糖尿病学会 糖尿病専門医・研修指導医 日本内分泌学会 内分泌代謝科専門医・指導医 日本肥満学会 肥満症専門医・指導医 日本動脈硬化学会 動脈硬化専門医・指導医 日本専門医機構　内分泌代謝・糖尿病内科領域専門研修指導医 日本医師会認定産業医
	日本糖尿病学会 学術評議員・近畿支部評議員 日本内分泌学会 評議員 日本肥満学会 評議員 日本動脈硬化学会 評議員
	2002年医科学研究応用財団研究助成 2003年日本内分泌学会若手研究奨励賞 2003年日本肥満学会若手研究奨励賞 2003年先進医薬研究振興財団研究助成 2003年財団法人病態代謝研究会研究助成 2004年日本心臓財団動脈硬化Update優秀賞 2004年細胞科学研究財団研究助成 2004年日本心臓財団研究助成 2005年井上研究奨励賞 2005年岡本研究奨励賞 2005年The 3rd Metabolic Syndrome Conference 若手研究奨励賞 2005年Research Award on Molecular and Cellular Cardiology 2005年かなえ医薬振興財団研究助成 2005年日本糖尿病財団研究助成 2005年総合健康推進財団研究助成 2006年第32回日本心臓財団研究奨励賞 2006年ソルト・サイエンス研究財団研究助成 2006年循環器学研究振興財団研究助成 2009年日本肥満学会学術奨励賞 2009年かなえ医薬振興財団研究助成 2012年日本内分泌学会研究奨励賞 2012年武田科学振興財団研究助成 2013年日本糖尿病財団研究助成 2013年鈴木謙三記念医科学応用研究財団研究助成 2014年大阪大学総長奨励賞
	温泉巡り、グルメ番組鑑賞
	Maeda N*, Funahashi T, Matsuzawa Y, Shimomura I: *Corresponding author Adiponectin, a unique adipocyte-derived factor beyond hormones Atherosclerosis. 292: 1-9, 2020 Kita S, Maeda N, Shimomura I: Interorgan communication by exosomes, adipose tissue, and adiponectin in metabolic syndrome J Clin Invest. 129: 4041-4049, 2019 Sato F, Maeda N*, Yamada T, Namazui H, Fukuda S, Natsukawa T, Nagao H, Murai J, Masuda S, Tanaka Y, Obata Y, Fujishima Y, Nishizawa H, Funahashi T, Shimomura I: *Corresponding author Association of Epicardial, Visceral, and Subcutaneous Fat With Cardiometabolic Diseases Circ J. 82: 502-508, 2018 Natsukawa T, Maeda N*, Fukuda S, Yamaoka M, Fujishima Y, Nagao H, Sato F, Nishizawa H, Sawano H, Hayashi Y, Funahashi T, Kai T, Shimomura I: *Corresponding author Significant Association of Serum Adiponectin and Creatine Kinase-MB Levels in ST-Segment Elevation Myocardial Infarction J Atheroscler Thromb. 24: 793-803, 2017 Fujishima Y, Maeda N*, Matsuda K, Masuda S, Mori T, Fukuda S, Sekimoto R, Yamaoka M, Obata Y, Kita S, Nishizawa H, Funahashi T, Ranscht B, Shimomura I: *Corresponding author Adiponectin association with T-cadherin protects against neointima proliferation and atherosclerosis FASEB J. 31: 1571-1583, 2017 Obata Y, Maeda N*, Yamada Y, Yamamoto K, Nakamura S, Yamaoka M, Tanaka Y, Masuda S, Nagao H, Fukuda S, Fujishima Y, Kita S, Nishizawa H, Funahashi T, Matsubara KI, Matsuzawa Y, Shimomura I: *Corresponding author Impact of visceral fat on gene expression profile in peripheral blood cells in obese Japanese subjects Cardiovasc Diabetol. 15:159, 2016 Sekimoto R, Fukuda S, Maeda N*, Tsushima Y, Matsuda K, Mori T, Nakatsuji H, Nishizawa H, Kishida K, Kikuta J, Maijima Y, Funahashi T, Ishii M, Shimomura I: *Corresponding author Visualized macrophage dynamics and significance of S100A8 in obese fat Proc Natl Acad Sci U S A. 112: E2058- E2066, 2015 Matsuda K, Fujishima Y, Maeda N*, Mori T, Hirata A, Sekimoto R, Tsushima Y, Masuda S, Yamaoka M, Inoue K, Nishizawa H, Kita S, Ranscht B, Funahashi T, Shimomura I: *Corresponding author Positive feedback regulation between adiponectin and T-cadherin impacts adiponectin levels in tissue and plasma of male mice Endocrinology. 156: 934-946, 2015 Yamaoka M, Maeda N*, Takayama Y, Sekimoto R, Tsushima Y, Matsuda K, Mori T, Inoue K, Nishizawa H, Tominaga M, Funahashi T, Shimomura I: *Corresponding author Adipose hypothermia in obesity and its association with period homolog 1, insulin sensitivity, and inflammation in fat PLoS One. 9: e112813, 2014 Inoue K, Maeda N*, Fujishima Y, Fukuda S, Nagao H, Yamaoka M, Hirata A, Nishizawa H, Funahashi T, Shimomura I: *Corresponding author Long-term impact of liraglutide, a glucagon-like peptide-1 (GLP-1) analogue, on body weight and glycemic control in Japanese type 2 diabetes: an observational study Diabetol Metab Syndr. 6: 95, 2014 Hibuse T, Maeda N*, Kishida K, Kimura T, Minami T, Takeshita E, Hirata A, Nakagawa Y, Kashine S, Oka A, Hayashi M, Nishizawa H, Funahashi T, Shimomura I: *Corresponding author A pilot three-month sitagliptin treatment increases serum adiponectin level in Japanese patients with type 2 diabetes mellitus--a randomized controlled trial START-J study Cardiovasc Diabetol. 13: 96, 2014 Mori T, Koyama Y, Maeda N*, Nakamura Y, Fujishima Y, Matsuda K, Funahashi T, Shimada S, Shimomura I: *Corresponding author Ultrastructural localization of adiponectin protein in vasculature of normal and atherosclerotic mice Sci Rep. 4: 4895, 2014 Inoue K, Maeda N*, Mori T, Sekimoto R, Tsushima Y, Matsuda K, Yamaoka M, Suganami T, Nishizawa H, Ogawa Y, Funahashi T, Shimomura I: *Corresponding author Possible involvement of Opa-interacting protein 5 in adipose proliferation and obesity PLoS One. 9: e87661, 2014 Fujishima Y, Maeda N*, Matsuda K, Komura N, Hirata A, Mori T, Sekimoto R, Tsushima Y, Nishizawa H, Funahashi T, Shimomura I: *Corresponding author Effect of adiponectin on cardiac β-catenin signaling pathway under angiotensin II infusion Biochem Biophys Res Commun. 444: 224-229, 2014 Maeda N*, Funahashi T, Shimomura I: *Corresponding author Cardiovascular-metabolic impact of adiponectin and aquaporin Endocr J. 60: 251-259, 2013 Mori T, Maeda N*, Inoue K, Sekimoto R, Tsushima Y, Matsuda K, Yamaoka M, Suganami T, Nishizawa H, Ogawa Y, Funahashi T, Shimomura I: *Corresponding author A novel role for adipose ephrin-B1 in inflammatory response PLoS One. 8: e76199, 2013 Komura N, Maeda N*, Mori T, Kihara S, Nakatsuji H, Hirata A, Tochino Y, Funahashi T, Shimomura I: Adiponectin protein exists in aortic endothelial cells *Corresponding author PLoS One. 8: e71271, 2013 Yamaoka M, Maeda N*, Nakamura S, Mori T, Inoue K, Matsuda K, Sekimoto R, Kashine S, Nakagawa Y, Tsushima Y, Fujishima Y, Komura N, Hirata A, Nishizawa H, Matsuzawa Y, Matsubara K, Funahashi T, Shimomura I: *Corresponding author Gene expression levels of S100 protein family in blood cells are associated with insulin resistance and inflammation Biochem Biophys Res Commun. 433: 450-455, 2013 Maeda N*: *Corresponding author Implications of aquaglyceroporins 7 and 9 in glycerol metabolism and metabolic syndrome Mol Aspects Med. 33: 665-675, 2012 Yamaoka M, Maeda N*, Nakamura S, Kashine S, Nakagawa Y, Hiuge-Shimizu A, Okita K, Imagawa A, Matsuzawa Y, Matsubara K, Funahashi T, Shimomura I: *Corresponding author A pilot investigation of visceral fat adiposity and gene expression profile in peripheral blood cells PLoS One. 7: e47377, 2012 Fujishima Y, Maeda N*, Inoue K, Kashine S, Nishizawa H, Hirata A, Kozawa J, Yasuda T, Okita K, Imagawa A, Funahashi T, Shimomura I: *Corresponding author Efficacy of liraglutide, a glucagon-like peptide-1 (GLP-1) analogue, on body weight, eating behavior, and glycemic control, in Japanese obese type 2 diabetes Cardiovasc Diabetol. 11: 107, 2012 Hirata A, Maeda N*, Nakatsuji H, Hiuge-Shimizu A, Okada T, Funahashi T, Shimomura I: *Corresponding author Contribution of glucocorticoid-mineralocorticoid receptor pathway on the obesity-related adipocyte dysfunction Biochem Biophys Res Commun. 419: 182-187, 2012 Inoue K, Maeda N*, Kashine S, Fujishima Y, Kozawa J, Hiuge-Shimizu A, Okita K, Imagawa A, Funahashi T, Shimomura I: *Corresponding author Short-term effects of liraglutide on visceral fat adiposity, appetite, and food preference: a pilot study of obese Japanese patients with type 2 diabetes Cardiovasc Diabetol. 10: 109, 2011 Hiuge-Shimizu A, Maeda N*, Hirata A, Nakatsuji H, Nakamura K, Okuno A, Kihara S, Funahashi T, Shimomura I: *Corresponding author Dynamic changes of adiponectin and S100A8 levels by the selective peroxisome proliferator-activated receptor-gamma agonist rivoglitazone Arterioscler Thromb Vasc Biol. 31: 792-799, 2011 Nakatsuji H, Maeda N*, Hibuse T, Hiuge A, Hirata A, Kuroda Y, Kishida K, Kihara S, Funahashi T, Shimomura I: *Corresponding author Reciprocal regulation of natriuretic peptide receptors by insulin in adipose cells Biochem Biophys Res Commun. 392: 100-105, 2010 Fujita K, Maeda N*, Kozawa J, Murano K, Okita K, Iwahashi H, Kihara S, Ishigami M, Omura M, Nakamura T, Shirai K, Yamamura T, Funahashi T, Shimomura I: *Corresponding author A case of adolescent hyperlipoproteinemia with xanthoma and acute pancreatitis, associated with decreased activities of lipoprotein lipase and hepatic triglyceride lipase. Intern Med. 49: 2467-2472, 2010 Hirata A, Maeda N*, Hiuge A, Hibuse T, Fujita K, Okada T, Kihara S, Funahashi T, Shimomura I: *Corresponding author Blockade of mineralocorticoid receptor reverses adipocyte dysfunction and insulin resistance in obese mice Cardiovasc Res. 84: 164-172, 2009 Hibuse T, Maeda N*, Nakatsuji H, Tochino Y, Fujita K, Kihara S, Funahashi T, Shimomura I: *Corresponding author The heart requires glycerol as an energy substrate through aquaporin 7, a glycerol facilitator Cardiovasc Res. 83: 34-41, 2009 Maeda N* (corresponding), Funahashi T, Shimomura I: *Corresponding author Metabolic impact of adipose and hepatic glycerol channels aquaporin 7 and aquaporin 9 Nat Clin Pract Endocrinol Metab. 4: 627-34, 2008. (2009/4〜Nature Reviews Endocrinology) Fujita K, Maeda N*, Sonoda M, Ohashi K, Hibuse T, Nishizawa H, Nishida M, Hiuge A, Kurata A, Kihara S, Shimomura I, Funahashi T: *Corresponding author Adiponectin protects against angiotensin II-induced cardiac fibrosis through activation of PPAR-alpha Arterioscler Thromb Vasc Biol. 28: 863-870, 2008 Hiuge A, Tenenbaum A, Maeda N*, Benderly M, Kumada M, Fisman EZ, Tanne D, Matas Z, Hibuse T, Fujita K, Nishizawa H, Adler Y, Motro M, Kihara S, Shimomura I, Behar S, Funahashi T: *Corresponding author Effects of peroxisome proliferator-activated receptor ligands, bezafibrate and fenofibrate, on adiponectin level Arterioscler Thromb Vasc Biol. 27: 635-641, 2007 Hibuse T, Maeda N* (corresponding), Nagasawa A, Funahashi T: *Corresponding author Aquaporins and glycerol metabolism Biochim Biophys Acta. 1758: 1004-1011, 2006 Hibuse T, Maeda N**, Funahashi T, Yamamoto K, Nagasawa A, Mizunoya W, Kishida K, Inoue K, Kuriyama H, Nakamura T, Fushiki T, Kihara S, Shimomura I: **Equally contributed to 1st author Aquaporin 7 deficiency is associated with development of obesity through activation of adipose glycerol kinase Proc Natl Acad Sci U S A. 102: 10993-10998, 2005 Maeda N, Funahashi T, Hibuse T, Nagasawa A, Kishida K, Kuriyama H, Nakamura T, Kihara S, Shimomura I, Matsuzawa Y: Adaptation to fasting by glycerol transport through aquaporin 7 in adipose tissue Proc Natl Acad Sci U S A. 101: 17801-17806, 2004 Maeda N, Shimomura I, Kishida K, Nishizawa H, Matsuda M, Nagaretani H, Furuyama N, Kondo H, Takahashi M, Arita Y, Komuro R, Ouchi N, Kihara S, Tochino Y, Okutomi K, Horie M, Takeda S, Aoyama T, Funahashi T, Matsuzawa Y: Diet-induced insulin resistance in mice lacking adiponectin/ACRP30 Nat Med. 8: 731-737, 2002 Maeda N, Takahashi M, Funahashi T, Kihara S, Nishizawa H, Kishida K, Nagaretani H, Matsuda M, Komuro R, Ouchi N, Kuriyama H, Hotta K, Nakamura T, Shimomura I, Matsuzawa Y: PPARgamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein Diabetes. 50: 2094-2099, 2001 Maeda N, Hiraoka H, Nakamura T, Matsuura F, Ouchi N, Nakata A, Kobayashi H, Yamashita S, Kameda-Takemura K, Matsuzawa Y: Acetylcholine-Induced Coronary Microvascular vasospasm in a Patient with Angina Pectoris and Normal Coronary Angiogram Angiology 48: 995-999, 1997